Structure Prediction · Model family Google DeepMind 3 Compare
↳ AlphaFold 2 / 3 has 3 matching version records.
Protein DNA RNA Ligand Prediction
2024 AlphaFold 3 Available / working Protein–ligand complexes · Protein–nucleic-acid complexes
2021 AlphaFold-Multimer Legacy / superseded Protein complex structure
2020 AlphaFold 2 Legacy / superseded Protein monomer structure · Protein structure confidence
Structure Prediction · Model family MIT (Barzilay & Jaakkola labs) 2 Compare
↳ Boltz-1 / Boltz-2 has 2 matching version records.
Protein DNA RNA Ligand Prediction Affinity prediction
2025 Boltz-2 Available / working Biomolecular complex structure · Binding-affinity prediction
2024 Boltz-1 Legacy / superseded Biomolecular complex structure
Structure Prediction · Model family Chai Discovery 2 Compare
↳ Chai-1 / Chai-2 has 2 matching version records.
Protein Antibody DNA RNA Prediction Generation
2025 Chai-2 Available / working Antibody design · Binder generation
2024 Chai-1 Legacy / superseded Multimodal biomolecular complex structure
Genomics, DNA & RNA · Model family Arc Institute + Stanford + NVIDIA 2 Compare
↳ Evo / Evo 2 has 2 matching version records.
DNA Generation Prediction Representation
2025 Evo 2 Available / working Genome-scale sequence modelling · Variant-effect and generation workflows
2024 Evo Legacy / superseded Long-context genomic sequence modelling
Structure Prediction · Model family OpenFold Consortium / Columbia 2 Compare
↳ OpenFold has 2 matching version records.
Protein DNA RNA Ligand Prediction Training
2026 OpenFold3 Preview In development / preview Protein complexes · Protein–ligand
2022 OpenFold (AF2 reproduction) Legacy / superseded Trainable open protein structure prediction · AlphaFold 2 reproduction
Protein & Binder Design · Model family Institute for Protein Design, UW 2 Compare
↳ ProteinMPNN / LigandMPNN has 2 matching version records.
Protein Ligand Metal DNA/RNA context Generation Inverse folding
2023 LigandMPNN Available / working Ligand-aware protein sequence design · Metal and nucleic-acid context
2022 ProteinMPNN Available / working Protein sequence design from backbone
Protein & Binder Design · Model family Institute for Protein Design, UW 2 Compare
↳ RFdiffusion has 2 matching version records.
Protein Molecule Generation Design
2025 RFdiffusion2 Available / working Atom-level enzyme design · Active-site scaffolding
2023 RFdiffusion Legacy / superseded De novo protein backbones · Binder design
Structure Prediction · Model family Institute for Protein Design, UW 2 Compare
↳ RoseTTAFold / All-Atom has 2 matching version records.
Protein Prediction
2024 RoseTTAFold All-Atom Available / working Protein–ligand complexes · Nucleic acids
2021 RoseTTAFold Legacy / superseded Protein structure prediction
Virtual Cells & Single-Cell · Model family Arc Institute 2 Compare
↳ State / Stack has 2 matching version records.
Cell Transcriptomics Perturbation Representation Prediction Simulation
2026 Stack Available / working In-context cell biology · Generalization to new biological conditions
2025 State Legacy / superseded Cell-state representation · Perturbation-response prediction
Antibodies & Biologics · Model family Absci 1 Compare
↳ Absci — Integrated Drug Creation has 1 matching version record.
Antibody Protein Generation Optimization Prediction
Pending Version history not yet curated Available / working Generation · Optimization
Genomics, DNA & RNA · Model family Google DeepMind 1 Compare
↳ AlphaGenome has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Availability not verified Generation · Prediction
Genomics, DNA & RNA · Model family Google DeepMind 1 Compare
↳ AlphaMissense has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Availability not verified Generation · Prediction
Protein & Binder Design · Model family Google DeepMind 1 Compare
↳ AlphaProteo has 1 matching version record.
Protein Generation Optimization
Pending Version history not yet curated Availability not verified Generation · Optimization
Protein Foundation & Representation · Model family Proteinea / academic collaborators 1 Compare
↳ Ankh has 1 matching version record.
Protein Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Platforms, Data & Infra · Platform / infrastructure Basecamp Research 1 Compare
↳ Basecamp Research (EDEN / BaseFold) has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Availability not verified Platform · Training
Platforms, Data & Infra · Platform / infrastructure BenevolentAI 1 Compare
↳ BenevolentAI has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Available / working Platform · Training
Antibodies & Biologics · Model family BigHat Biosciences 1 Compare
↳ BigHat Biosciences — Milliner has 1 matching version record.
Antibody Protein Generation Optimization Prediction
Pending Version history not yet curated Available / working Generation · Optimization
Genomics, DNA & RNA · Model family Deep Genomics 1 Compare
↳ BigRNA has 1 matching version record.
RNA Transcriptomics Representation Prediction Design
Pending Version history not yet curated Available / working Representation · Prediction
Protein & Binder Design · Model family MIT / Boltz team 1 Compare
↳ BoltzGen has 1 matching version record.
Protein Peptide Small molecule Generation Optimization
2025 BoltzGen Available / working All-atom binder design · Target-conditioned molecular generation
Genomics, DNA & RNA · Model family Calico / academic collaborators 1 Compare
↳ Borzoi has 1 matching version record.
DNA RNA Prediction Variant effect
Pending Version history not yet curated Available / working Prediction · Variant effect
Genomics, DNA & RNA · Model family Cornell / Tri Dao collaborators 1 Compare
↳ Caduceus has 1 matching version record.
DNA Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Virtual Cells & Single-Cell · Model family Google Research + Yale 1 Compare
↳ Cell2Sentence (C2S-Scale) has 1 matching version record.
Cell Transcriptomics Simulation Prediction Representation
Pending Version history not yet curated Availability not verified Simulation · Prediction
Small-Molecule & Chemistry · Platform / infrastructure Insilico Medicine 1 Compare
↳ Chemistry42 / Pharma.AI has 1 matching version record.
Molecule Generation Prediction Docking
Pending Version history not yet curated Available / working Generation · Prediction
Protein & Binder Design · Model family Generate Biomedicines 1 Compare
↳ Chroma has 1 matching version record.
Protein Generation Optimization
Pending Version history not yet curated Available / working Generation · Optimization
Tissue, Pathology & Imaging · Model family Mahmood Lab 1 Compare
↳ CONCH has 1 matching version record.
Histopathology image Text Representation Retrieval Prediction
Pending Version history not yet curated Availability not verified Representation · Retrieval
Platforms, Data & Infra · Platform / infrastructure Cradle 1 Compare
↳ Cradle Bio has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Availability not verified Platform · Training
Virtual Cells & Single-Cell · Platform / infrastructure Chan Zuckerberg Initiative 1 Compare
↳ CZI Virtual Cells (rBio, TranscriptFormer) has 1 matching version record.
Transcriptomics Protein Multimodal Platform Training Model ecosystem
Pending Version history not yet curated Availability not verified Platform · Training
Small-Molecule & Chemistry · Model family MIT (Barzilay & Jaakkola labs) 1 Compare
↳ DiffDock has 1 matching version record.
Molecule Generation Prediction Docking
Pending Version history not yet curated Available / working Generation · Prediction
Genomics, DNA & RNA · Model family Multi-institution research team 1 Compare
↳ DNABERT-2 has 1 matching version record.
DNA Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Genomics, DNA & RNA · Model family Google DeepMind 1 Compare
↳ Enformer has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Availability not verified Generation · Prediction
Protein Foundation & Representation · Model family Meta AI (FAIR) 1 Compare
↳ ESM-2 has 1 matching version record.
Protein Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Protein & Binder Design · Model family EvolutionaryScale (now CZ Biohub) 1 Compare
↳ ESM3 has 1 matching version record.
Protein Representation Generation Completion
2024 ESM3 Available / working Protein sequence · Protein structure
Structure Prediction · Model family Meta AI (FAIR) 1 Compare
↳ ESMFold has 1 matching version record.
Protein Prediction
Pending Version history not yet curated Available / working Prediction · Protein
Small-Molecule & Chemistry · Model family Genesis Therapeutics 1 Compare
↳ GEMS has 1 matching version record.
Molecule Generation Prediction Docking
Pending Version history not yet curated Available / working Generation · Prediction
Genomics, DNA & RNA · Model family Broad Institute 1 Compare
↳ Geneformer has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Availability not verified Generation · Prediction
Platforms, Data & Infra · Platform / infrastructure Ginkgo Bioworks 1 Compare
↳ Ginkgo Bioworks (Datapoints / AI Models) has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Availability not verified Platform · Training
Genomics, DNA & RNA · Model family Poetsch Lab / collaborators 1 Compare
↳ GROVER has 1 matching version record.
DNA Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Tissue, Pathology & Imaging · Model family Bioptimus 1 Compare
↳ H-Optimus has 1 matching version record.
Histopathology image Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Structure Prediction · Model family PaddleHelix / Baidu 1 Compare
↳ HelixFold3 has 1 matching version record.
Protein DNA RNA Ligand Prediction
Pending Version history not yet curated Availability not verified Prediction · Protein
Genomics, DNA & RNA · Model family Stanford (Hazy Research) 1 Compare
↳ HyenaDNA has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Available / working Generation · Prediction
Antibodies & Biologics · Model family Johns Hopkins (Gray Lab) 1 Compare
↳ IgLM / AntiBERTy has 1 matching version record.
Antibody Protein Generation Optimization Prediction
Pending Version history not yet curated Available / working Generation · Optimization
Antibodies & Biologics · Model family LabGenius 1 Compare
↳ LabGenius — EVA has 1 matching version record.
Antibody Protein Generation Optimization Prediction
Pending Version history not yet curated Available / working Generation · Optimization
Protein & Binder Design · Model family Latent Labs 1 Compare
↳ Latent-X has 1 matching version record.
Protein Generation Optimization
Pending Version history not yet curated Availability not verified Generation · Optimization
Genomics, DNA & RNA · Model family BioMap / collaborators 1 Compare
↳ LucaOne has 1 matching version record.
DNA RNA Protein Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Small-Molecule & Chemistry · Model family NVIDIA 1 Compare
↳ MegaMolBART has 1 matching version record.
Molecule Representation Generation
Pending Version history not yet curated Availability not verified Representation · Generation
Small-Molecule & Chemistry · Model family NVIDIA 1 Compare
↳ MolMIM has 1 matching version record.
Molecule Representation Generation
Pending Version history not yet curated Availability not verified Representation · Generation
Antibodies & Biologics · Model family Nabla Bio 1 Compare
↳ Nabla Bio — JAM has 1 matching version record.
Antibody Protein Generation Optimization Prediction
Pending Version history not yet curated Available / working Generation · Optimization
Small-Molecule & Chemistry · Model family Iambic Therapeutics 1 Compare
↳ NeuralPLexer / Enchant has 1 matching version record.
Molecule Generation Prediction Docking
Pending Version history not yet curated Availability not verified Generation · Prediction
Spatial & Tissue Systems · Model family Spatial biology research team 1 Compare
↳ Nicheformer has 1 matching version record.
Spatial transcriptomics Cell Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Spatial & Tissue Systems · Model family Spatial-omics research community 1 Compare
↳ Novae has 1 matching version record.
Spatial transcriptomics Representation Clustering Prediction
Pending Version history not yet curated Availability not verified Representation · Clustering
Genomics, DNA & RNA · Model family InstaDeep (BioNTech) 1 Compare
↳ Nucleotide Transformer has 1 matching version record.
DNA Generation Prediction Representation
Pending Version history not yet curated Available / working Generation · Prediction
Small-Molecule & Chemistry · Platform / infrastructure Numerion Labs 1 Compare
↳ Numerion AI Chemistry Platform has 1 matching version record.
Molecule Generation Prediction Docking
Pending Version history not yet curated Available / working Generation · Prediction
Small-Molecule & Chemistry · Platform / infrastructure NVIDIA 1 Compare
↳ NVIDIA BioNeMo has 1 matching version record.
Molecule Protein DNA RNA Platform Training Inference
Pending Version history not yet curated Available / working Platform · Training
Platforms, Data & Infra · Platform / infrastructure Owkin 1 Compare
↳ Owkin has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Availability not verified Platform · Training
Platforms, Data & Infra · Platform / infrastructure Profluent Bio 1 Compare
↳ Profluent (ProGen3 / OpenCRISPR) has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Availability not verified Platform · Training
Protein & Binder Design · Model family Salesforce Research → Profluent 1 Compare
↳ ProGen / ProGen2 / ProGen3 has 1 matching version record.
Protein Generation Optimization
Pending Version history not yet curated Available / working Generation · Optimization
Structure Prediction · Model family ByteDance 1 Compare
↳ Protenix has 1 matching version record.
Protein Prediction
Pending Version history not yet curated Available / working Prediction · Protein
Protein Foundation & Representation · Model family Rostlab 1 Compare
↳ ProtT5 has 1 matching version record.
Protein Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Tissue, Pathology & Imaging · Model family Microsoft Research / Providence 1 Compare
↳ Prov-GigaPath has 1 matching version record.
Histopathology image Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Platforms, Data & Infra · Platform / infrastructure Recursion Pharmaceuticals 1 Compare
↳ Recursion (LOWE + Phenomics) has 1 matching version record.
Multimodal Platform Training Prediction
Pending Version history not yet curated Available / working Platform · Training
Antibodies & Biologics · Model family Institute for Protein Design, UW 1 Compare
↳ RFantibody has 1 matching version record.
Antibody Protein Generation Optimization
2025 RFantibody Available / working Epitope-specific antibody generation · De novo antibody structure/sequence design
RNA Models & Design · Model family University of Zagreb / A*STAR collaborators 1 Compare
↳ RiNALMo has 1 matching version record.
RNA Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
RNA Models & Design · Model family ML4Bio / academic collaborators 1 Compare
↳ RNA-FM has 1 matching version record.
RNA Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Protein Foundation & Representation · Model family Westlake / Zhejiang collaborators 1 Compare
↳ SaProt has 1 matching version record.
Protein Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Virtual Cells & Single-Cell · Model family Tsinghua / BioMap 1 Compare
↳ scFoundation has 1 matching version record.
Cell Transcriptomics Simulation Prediction Representation
Pending Version history not yet curated Availability not verified Simulation · Prediction
Virtual Cells & Single-Cell · Model family University of Toronto (Bo Wang Lab) 1 Compare
↳ scGPT has 1 matching version record.
Cell Transcriptomics Simulation Prediction Representation
Pending Version history not yet curated Available / working Simulation · Prediction
Small-Molecule & Chemistry · Platform / infrastructure Schrödinger, Inc. 1 Compare
↳ Schrödinger Platform has 1 matching version record.
Molecule Protein Simulation Prediction Platform
Pending Version history not yet curated Available / working Simulation · Prediction
Virtual Cells & Single-Cell · Model family Genentech 1 Compare
↳ SCimilarity has 1 matching version record.
Transcriptomics Cell Representation Prediction
Pending Version history not yet curated Available / working Representation · Prediction
Tissue, Pathology & Imaging · Model family Mahmood Lab / collaborators 1 Compare
↳ TITAN has 1 matching version record.
Histopathology image Text Representation Retrieval Prediction
Pending Version history not yet curated Availability not verified Representation · Retrieval
Virtual Cells & Single-Cell · Model family Chan Zuckerberg Initiative 1 Compare
↳ TranscriptFormer has 1 matching version record.
Transcriptomics Cell Representation Generation Prediction
Pending Version history not yet curated Availability not verified Representation · Generation
Tissue, Pathology & Imaging · Model family Mahmood Lab / Brigham and Women’s Hospital 1 Compare
↳ UNI / UNI2 has 1 matching version record.
Histopathology image Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Small-Molecule & Chemistry · Model family DP Technology / DeepModeling 1 Compare
↳ Uni-Mol / Uni-Mol2 has 1 matching version record.
Molecule Representation Generation
Pending Version history not yet curated Available / working Representation · Generation
RNA Models & Design · Model family Academic RNA foundation-model collaborators 1 Compare
↳ UNI-RNA has 1 matching version record.
RNA Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Virtual Cells & Single-Cell · Model family Stanford / collaborators 1 Compare
↳ Universal Cell Embeddings (UCE) has 1 matching version record.
Transcriptomics Cell Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
AI-Native Discovery Cos. · Platform / infrastructure Recursion Pharmaceuticals 1 Compare
↳ Valence Labs (MolGPS / LOWE) has 1 matching version record.
Multimodal Platform Discovery
Pending Version history not yet curated Available / working Platform · Discovery
Tissue, Pathology & Imaging · Model family Paige / Microsoft Research collaborators 1 Compare
↳ Virchow / Virchow2 has 1 matching version record.
Histopathology image Representation Prediction
Pending Version history not yet curated Availability not verified Representation · Prediction
Protein Foundation & Representation · Model family BioMap / Tsinghua collaborators 1 Compare
↳ xTrimoPGLM has 1 matching version record.
Protein Representation Prediction Generation
Pending Version history not yet curated Availability not verified Representation · Prediction