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Versioned registry · superseded

AlphaFold 2

Established the modern deep-learning structure-prediction baseline.

Model familyAlphaFold 2 / 3
OrganizationGoogle DeepMind
Release year2020
Version2
AccessLimited open access
CheckpointPublic AlphaFold 2 parameters
LicenseAF2 open (Apache-2.0); AF3 code open for academia, weights on request
Source typepeer-reviewed

Scientific scope

  • Protein monomer structure
  • Protein structure confidence

Capabilities added

  • End-to-end structure prediction
  • Evoformer reasoning over MSA and residue pairs
Model lineage

Related releases in the same family.

current

AlphaFold 3

Replaced the AF2 structure module with a diffusion-based architecture and broadened supported complex types.

superseded

AlphaFold-Multimer

Extended the AlphaFold 2 family from monomers to protein assemblies.

superseded

AlphaFold 2

Established the modern deep-learning structure-prediction baseline.