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Versioned registry · current

AlphaFold 3

Replaced the AF2 structure module with a diffusion-based architecture and broadened supported complex types.

Model familyAlphaFold 2 / 3
OrganizationGoogle DeepMind
Release year2024
Version3
AccessLimited open access
CheckpointServer and released code/weights subject to current access terms
LicenseAF2 open (Apache-2.0); AF3 code open for academia, weights on request
Source typepeer-reviewed

Scientific scope

  • Protein–ligand complexes
  • Protein–nucleic-acid complexes
  • All-atom biomolecular structure

Capabilities added

  • Broader molecular entity support
  • Diffusion-based coordinate generation
Model lineage

Related releases in the same family.

current

AlphaFold 3

Replaced the AF2 structure module with a diffusion-based architecture and broadened supported complex types.

superseded

AlphaFold-Multimer

Extended the AlphaFold 2 family from monomers to protein assemblies.

superseded

AlphaFold 2

Established the modern deep-learning structure-prediction baseline.